If you are already taking any medicines, including those bought without a prescription and herbal medicines, you should always get advice from your doctor or pharmacist before taking any other medicines as well, to make sure the combination is safe.

So, if you are taking any medicines or painkillers, including the one you bought to consume without a prescription- then it can be very harmful. Make sure you always get an advice from your physician before you go to buy Co-codamol UK or any other painkiller.

Well, this is very important that you do not consume any other medicines that have paracetamol as a part of its combination with Co-codamol, as this can result in exceeding the dosage recommended by your doctor, Several cold or flu remedies tend to contain paracetamol as a basic salt, therefore, just make sure to check the salts of other medicines before consuming them with Co-codamol. It is fine to take ibuprofen or medicines like aspirin with co-codamol. However, do not take it with medicines like tramacet or co-dydramol

So, in case you take co-codamol within the hour before or 6 hours after taking salts as mentioned above- then it is likely to be less effective. Also, do not take medicines like cholestyramine with co-codamol, as the medicine tends to reduce the absorption of paracetamol in the body. In addition to it, the antidiabetic medicines like exenatide, liraglutide or lixisenatide might slow down the absorption of paracetamol into your blood. Therefore, always consult your doctor before you plan to buy Co-codamol UK.  Even the high dosage of the anticancer medicine imatinib can also prevent the breakdown of paracetamol. So, in case you are consuming imatinib do not take Co-codamol without consulting your doctor first.

Last but not the least, if you are going through any treatment like chemotherapy or taking medicine like busulfan- well, then you should not consume co-codamol without discussing your issues with your physician or your pharmacist. Always remember, is you take paracetamol with or in 72 hours before your chemotherapy or with busulfan, then you are likely to have some serious chances to develop the side effects.